LIGAND INDUCED CONFORMATIONAL CHANGES OF THE HUMAN SEROTONIN TRANSPORTER REVEALED BY MOLECULAR DYNAMICS SIMULATIONS.

Ligand induced conformational changes of the human serotonin transporter revealed by molecular dynamics simulations.

The competitive inhibitor copyright and the non-competitive inhibitor ibogaine induce different conformational states of the human serotonin transporter.It has been shown from accessibility experiments that copyright mainly induces an outward-facing conformation, while the non-competitive inhibitor ibogaine, and its active metabolite noribogaine, h

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Thermally-Latent Curing Agents for Epoxy Resins: A Review

Epoxy PATCHOULI resins are widely used in composites, aerospace, construction, electronic, adhesive and coatings industries due to their high physical and mechanical, thermal resistance, electrical and chemical properties.For curing epoxy resins, a chemical material, called curing agent or hardener, must be used.Curing agents have strong effect on

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Tuning Ferulic Acid Solubility in Choline-Chloride- and Betaine-Based Deep Eutectic Solvents: Experimental Determination and Machine Learning Modeling

Deep eutectic solvents (DES) represent a promising class of green solvents, offering particular utility in the extraction and development of new formulations of natural compounds such as ferulic acid (FA).The experimental phase of the study undertook a systematic investigation of the solubility of FA in DES, comprising choline chloride or betaine a

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